Prognostic Value of N-terminal Probrain Natriuretic Peptide for Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis

Table 3

Subgroup analysis and metaregression analyses of NT-proBNP.

	Subgroup	Studies ()	Sensitivity	P1	Specificity	P2
Tested day	Day 1	5	0.77 [0.69-0.85]	0.01	0.82 [0.73-0.92]	0.59
	Non-day 1	2	0.81 [0.72-0.90]		0.65 [0.42-0.88]
Tested method	Elecsys 2010 analyzer	5	0.81 [0.74-0.88]	0.30	0.77 [0.64-0.91]	0.41
	Non-Elecsys 2010 analyzer	2	0.73 [0.60-0.85]		0.81 [0.63-0.99]
Endpoint	28 d mortality	5	0.80 [0.73-0.88]	0.11	0.85 [0.79-0.91]	0.41
	Non-28d mortality	2	0.74 [0.65-0.84]		0.58 [0.46-0.69]
Cut-off points	>1800 pg/mL	3	0.76 [0.68-0.84]	0.00	0.64 [0.52-0.77]	0.00
	<1800 pg/mL or no data provided	4	0.81 [0.73-0.89]		0.87 [0.80-0.94]