Molecular Mechanism of HSF1-Upregulated ALDH2 by PKC in Ameliorating Pressure Overload-Induced Heart Failure in Mice

Figure 3

The relative HSF1, ALDH2, and beta-MHC expression levels of neonatal mouse cardiomyocytes after mechanical stretch in vitro (a, b) The relative HSF1, ALDH2 mRNA, and protein levels of neonatal mouse cardiomyocytes (control: cardiomyocytes without mechanical stretch; MS: cardiomyocytes with mechanical stretch 48 h) (c, d) The relative HSF1, ALDH2, and beta-MHC mRNA and protein levels of neonatal mouse cardiomyocytes (control: cardiomyocytes without mechanical stretch; MS: cardiomyocytes with mechanical stretch 48 h; Ad-HSF1-shRNA+MS: cardiomyocytes infected by adenovirus-expressing HSF1 shRNA with mechanical stretch 48 h; Ad-HSF1+MS: cardiomyocytes infected by adenovirus-expressing HSF1 with mechanical stretch 48 h). ). , .

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