Association between Neck Circumference and the Risk of Decreased Estimated Glomerular Filtration Rate in the General Population of China: A Cross-Sectional Study

Table 6

The association between neck circumference and the risk of decreased eGFR in subgroups.

Variable	Q1	Q2	value	Q3	value	Q4	value
		OR (95% CI)		OR (95% CI)		OR (95% CI)
Female
Blood glucose^a
Normal	1.00 (reference)	1.17 (0.90-1.50)	0.238	1.49 (1.04-2.13)	0.029	1.18 (0.82-1.69)	0.380
Prediabetes	1.00 (reference)	1.30 (0.89-1.89)	0.170	1.43 (0.89-2.29)	0.142	1.81 (1.13-2.88)	0.013
Diabetes	1.00 (reference)	0.99 (0.68-1.43)	0.944	1.01 (0.63-1.63)	0.963	1.09 (0.69-1.71)	0.721
Blood pressure^b
Normal	1.00 (reference)	1.17 (0.82-1.68)	0.383	1.41 (0.83-2.40)	0.208	1.42 (0.83-2.46)	0.203
Prehypertension	1.00 (reference)	1.21 (0.86-1.70)	0.285	1.45 (0.93-2.26)	0.105	1.30 (0.83-2.02)	0.253
Hypertension	1.00 (reference)	1.15 (0.87-1.52)	0.317	1.27 (0.89-1.80)	0.183	1.33 (0.94-1.86)	0.104
BMI^c
	1.00 (reference)	1.06 (0.83-1.37)	0.637	1.25 (0.75-2.09)	0.392	1.31 (0.80-2.17)	0.288
	1.00 (reference)	1.18 (0.89-1.57)	0.251	1.28 (0.93-1.75)	0.126	1.22 (0.91-1.64)	0.181
Serum uric acid^d
	1.00 (reference)	1.21 (1.00-1.46)	0.049	1.58 (1.23-2.03)	<0.000	1.36 (1.06-1.75)	0.017
	1.00 (reference)	1.03 (0.57-1.85)	0.928	0.72 (0.35-1.46)	0.357	1.68 (0.86-3.28)	0.129
Cardiovascular disease^e
No	1.00 (reference)	1.18 (0.99-1.42)	0.065	1.38 (1.08-1.75)	0.009	1.42 (1.12-1.80)	0.003
Yes	1.00 (reference)	1.28 (0.44-3.70)	0.650	1.55 (0.44-5.46)	0.500	2.92 (0.81-10.58)	0.103
Male
Blood glucose^a
Normal	1.00 (reference)	1.24 (0.88-1.75)	0.229	1.32 (0.87-2.01)	0.186	1.45 (0.84-2.48)	0.181
Prediabetes	1.00 (reference)	1.05 (0.64-1.72)	0.844	1.22 (0.70-2.14)	0.488	2.26 (1.12-4.57)	0.024
Diabetes	1.00 (reference)	1.37 (0.88-2.12)	0.160	1.58 (0.99-2.53)	0.056	1.81 (1.02-3.20)	0.041
Blood pressure^b
Normal	1.00 (reference)	1.29 (0.71-2.32)	0.400	1.36 (0.63-2.91)	0.433	1.67 (0.58-4.78)	0.340
Prehypertension	1.00 (reference)	1.44 (0.93-2.24)	0.103	1.09 (0.65-1.83)	0.755	2.05 (1.06-3.96)	0.034
Hypertension	1.00 (reference)	1.15 (0.83-1.60)	0.399	1.51 (1.06-2.16)	0.024	1.57 (1.02-2.42)	0.043
BMI^c
	1.00 (reference)	1.01 (0.71-1.43)	0.978	0.89 (0.51-1.58)	0.696	1.26 (0.21-7.60)	0.804
	1.00 (reference)	1.62 (1.14-2.30)	0.008	1.79 (1.26-2.54)	0.001	2.09 (1.43-3.04)	<0.000
Serum uric acid^d
	1.00 (reference)	1.33 (1.04-1.70)	0.023	1.50 (1.13-1.99)	0.005	1.64 (1.15-2.35)	0.007
	1.00 (reference)	1.05 (0.51-2.15)	0.895	1.34 (0.62-2.89)	0.461	2.31 (0.93-5.77)	0.073
Cardiovascular disease^e
No	1.00 (reference)	1.35 (1.07-1.71)	0.013	1.47 (1.12-1.92)	0.006	1.72 (1.22-2.42)	0.002
Yes	1.00 (reference)	0.79 (0.29-2.10)	0.630	1.21 (0.42-3.46)	0.728	3.94 (1.04-14.99)	0.044

Model a: adjusted for age, BMI, WHR, SBP, DBP, pulse, TG, HDL, ALT, γ-GGT, education level, cardiovascular disease, serum uric acid, smoking, and drinking. Model b: adjusted for age, WHR, BMI, HbA1c, FPG, PBG, pulse, TG, HDL, ALT, γ-GGT, education level, cardiovascular disease, serum uric acid, smoking, and drinking. Model c: adjusted for age, WHR, SBP, DBP, pulse, HbA1c, FPG, PBG, TG, HDL, ALT, γ-GGT, education level, cardiovascular disease, serum uric acid, smoking, and drinking. Model d: adjusted for age, WHR, BMI, SBP, DBP, pulse, HbA1c, FPG, PBG, TG, HDL, ALT, γ-GGT, education level, cardiovascular disease, smoking, and drinking. Model e: adjusted for age, WHR, BMI, SBP, DBP, pulse, HbA1c, FPG, PBG, TG, HDL, ALT, γ-GGT, education level, serum uric acid, smoking, and drinking. Abbreviations: eGFR: estimated glomerular filtration rate; OR: odds ratio; CI: confidence interval; BMI: body mass index; WHR: waist-to-hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: hemoglobin A1c; FBG: fasting blood glucose; PBG: postprandial blood glucose; ALT: alanine transaminase; γ-GGT: γ-glutamyl transpeptidase; TG: triglyceride; HDL: high-density lipoprotein cholesterol.