Optimization of Ultrasound-Assisted Extraction of Flavonoids from <i>Celastrus hindsii</i> Leaves Using Response Surface Methodology and Evaluation of Their Antioxidant and Antitumor Activities

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_center" colspan="5">IC<sub>50</sub> values of antitumor effect of <i>C. hindsii</i> leaf extract (<i>μ</i>g/mL)</td></tr><tr class="thead"><td class="align_left">Sample</td><td class="align_center">MCF7</td><td class="align_center">A549</td><td class="align_center">HeLa</td><td class="align_center">HK2</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left"><i>C. hindsii</i></td><td class="align_center">88.1 ± 2.1</td><td class="align_center">120.4 ± 4.1</td><td class="align_center">118.4 ± 2.4</td><td class="align_center">&gt;200</td></tr><tr><td class="align_left">Cisplatin</td><td class="align_center">&gt;20</td><td class="align_center">2.3 ± 0.4</td><td class="align_center">6.7 ± 0.9</td><td class="align_center">1.9 ± 0.7</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>The results are expressed as mean ± SD of three independent experiments (<i>n</i> = 3).<br/></div></td></tr></table>

<div>Cytotoxic activity of <i>C. hindsii</i> leaf extract.</div>

BioMed Research International

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Table 5

Table 5: Optimization of Ultrasound-Assisted Extraction of Flavonoids from <i>Celastrus hindsii</i> Leaves Using Response Surface Methodology and Evaluation of Their Antioxidant and Antitumor Activities 

Table 5 | Optimization of Ultrasound-Assisted Extraction of Flavonoids from Celastrus hindsii Leaves Using Response Surface Methodology and Evaluation of Their Antioxidant and Antitumor Activities 