Circular RNA circ-CCAC1 Facilitates Adrenocortical Carcinoma Cell Proliferation, Migration, and Invasion through Regulating the miR-514a-5p/C22orf46 Axis

Figure 2

circ-CCAC1 facilitates ACC cell progression. (a) Relative expression of circ-CCAC1 was detected by RT-qPCR after transfection. (b) Relative expression of ERBB2 mRNA was detected by RT-qPCR after transfection. (c) Cell viability was detected after downregulating circ-CCAC1 in H295R cells by CCK-8. (d) Cell viability was detected after upregulating circ-CCAC1 in SW-13 cells by CCK-8. (e) Clone-forming ability was detected after downregulating circ-CCAC1 in H295R cells by colony formation assay. (f) Clone-forming ability was detected after upregulating circ-CCAC1 in SW-13 cells by colony formation assay. (g) Cell apoptosis was detected after downregulating circ-CCAC1 in H295R cells by AO/EB staining assay. (h) Cell apoptosis was detected after upregulating circ-CCAC1 in SW-13 cells by AO/EB staining assay. (i) Cell migration and invasion was detected after downregulating circ-CCAC1 in H295R cells by Transwell assay. (j) Cell migration and invasion were detected after upregulating circ-CCAC1 in SW-13 cells by Transwell assay. , .

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