[Retracted] High-Fat Diet Promotes DSS-Induced Ulcerative Colitis by Downregulated FXR Expression through the TGFB Pathway

Figure 2

FXR extenuate the tissue damage in DSS-induced mice: (a) body weight change in mice on combination treatment with DSS, HFD, FexD, and TGFBRI inhibitor SB431542 (Selleck) for 2 weeks; (b) DAI score change in mice on combination treatment with DSS, HFD, FexD, and TGFBRI inhibitor SB431542 for 2 weeks; (c) total bile acid concentration of serum in four experiment groups, respectively. , , and and for each group; (d) representative images of five groups’ colonic tissue stained with hematoxylin and eosin (H&E; upper) are shown. The bar represents 50 μm and 20 μm.

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