Deterioration of Health-Related Quality of Life Scores under Treatment Predicts Longer Survival
Table 3
Univariate and multivariate analyses according to Cox’s proportional hazards model for sociodemographic and clinical variables and HRQoL scores at baseline.
Univariate analysis
Multivariate analysis
Hazard ratio
95% C.I.
Hazard ratio
95% C.I.
T category (T1/T2 () vs. T3/T4 ())
1.141
0.743–1.753
0.547
—
—
—
N category (N0 () vs. N+ ())
1.351
0.857–2.13
0.195
1.415
0.918–2.182
0.116
M category (M0 () vs. M+ ())
2.334
1.471–3.703
0.0003
2.743
1.829–4.144
<0.0001
Gender (male () vs. female ())
1.096
0.724–1.661
0.665
—
—
—
Age (<60 years () vs. >60 years ())
1.887
1.248–2.853
0.003
2.059
1.379–3.072
0.0004
Physical functioning (above () vs. below median ())
1.533
0.932–2.521
0.093
1.299
0.835–2.019
0.246
Role functioning (above (] vs. below median ())
0.774
0.497–1.206
0.258
—
—
—
Global health status/QoL (above () vs. below median ())
