Overexpression of BMPER in Ovarian Cancer and the Mechanism by which It Promotes Malignant Biological Behavior in Tumor Cells

<div>Changes in the expression of PCNA, Bax, Bcl-2, MMP2, and MMP9 in CAOV3 and OVCAR3 cells after transfection of BMPER siRNA. Western blot showed knock down of BMPER gene by siRNA reduced the expressions of PCNA, Bcl-2, MMP2, and MMP9, while the level of proapoptotic protein Bax was increased after that. GAPDH was used as the internal control. 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BioMed Research International

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Figure 4

Figure 4: Overexpression of BMPER in Ovarian Cancer and the Mechanism by which It Promotes Malignant Biological Behavior in Tumor Cells 