Review Article
Clinical Significance of PIK3CA Gene in Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis
Table 3
Associations of PIK3CA expression with clinicopathological characteristics in non-small-cell lung cancer.
| | Author | Sex (M vs. F) | Age (≥65 vs. <65) | Differentiation (lower vs. higher) | Lymph node metastasis (+ vs. -) | TNM (advanced vs. limited) | Smoking history (yes vs. no) |
| | Endoh [16] | — | — | | — | — | — | | Iijima [19] | 1.241 (0.180-8.546) | 0.981 (0.236-4.083) | 0.627 (0.195-2.021) | 0.703 (0.200-2.472) | 0.627 (0.195-2.021) | 0.900 (0.136-5.945) | | Toschi [20] | 2.232 (1.267-3.934) | | 1.384 (1.035-1.851) | | 0.886 (0.654-1.200) | 3.091 (1.208-7.911) | | Overall ( (95% CI), ; , ) | 1.39 (0.24-7.89), 0.714; 0.0, 0.796 | — | 1.32 (1.00-1.75), 0.053; 39.7, 0.198 | — | 0.87 (0.65-1.16), 0.34; 0.0, 0.575 | 2.42 (1.04-5.61), 0.040; 23.9, 0.252 |
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RR: relative risk; CI: confidence interval; M: male; F: female; TNM: tumor-node-metastasis.
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