Utility of Plasma GDF-15 for Diagnosis and Prognosis Assessment of ICU-Acquired Weakness in Mechanically Ventilated Patients: Prospective Observational Study
Table 1
Comparison of baseline levels and clinical features between the two groups.
ICU-AW group (n = 50)
Non-ICU-AW group (n = 45)
t/χ2
value
Baseline characteristics
Age (years)
58.75 ± 13.58
60.32 ± 15.63
0.524
0.602
Male/total
32/50
29/45
0.045
0.964
Weight (kg)
61.43 ± 8.93
59.57 ± 11.68
0.877
0.383
BMI (kg/m2)
23.79 ± 3.41
24.47 ± 4.54
0.831
0.408
SOFA
8.23 ± 3.18
7.21 ± 3.67
1.451
0.150
APACHE II
16.35 ± 7.21
15.79 ± 8.12
0.356
0.723
Smoking history
18/50
15/45
0.001
0.983
Comorbidities
22/50
18/45
0.003
0.956
Cause of MV
Pneumonia
12/50
13/45
0.540
0.589
AECOPD
19/50
17/45
0.022
0.982
Pulmonary contusion
7/50
6/45
0.094
0.925
ARDS
6/50
4/45
0.493
0.622
Others
6/50
5/45
0.135
0.893
Length of MV (h)
196.68 ± 51.36
167.52 ± 78.72
2.159
0.033
ICU length of stay (days)
11.25 ± 3.37
9.76 ± 2.31
2.486
0.015
Hospital length of stay (days)
20.54 ± 6.37
17.76 ± 4.93
2.359
0.020
Data are mean ± standard deviation or number/total. Comorbidities include hypertension, diabetes, chronic kidney disease, cirrhosis, and history of trauma surgery. BMI: body mass index, SOFA: sequential organ failure assessment, APACHEII : Acute Physiology and Chronic Health Evaluation II, MV: mechanical ventilation, AECOPD: acute exacerbation of chronic obstructive pulmonary disease, ARDS: acute respiratory distress syndrome.
