Antimania-Like Effect of Panax ginseng Regulating the Glutamatergic Neurotransmission in REM-Sleep Deprivation Rats
Table 2
Different expressions of glutamatergic synapse and amphetamine addiction pathway genes in the control, sleep deprivation (SD), and Panax ginseng (PG-) treated SD rats.
Gene
Description
FC
SD+PG/S
SD/control
Glutamatergic synapse
Slc1a3
Solute carrier family 1 member 3
5.132
-3.718
Slc1a2
Solute carrier family 1 (glial high-affinity glutamate transporter), member 2
2.181
-1.18
Adcy1
Adenylate cyclase 1 (brain)
3.268
-1.125
Grik3
Glutamate ionotropic receptor kainate type subunit 3
2.032
1.517
Grin3a
Glutamate ionotropic receptor NMDA type subunit 3A
2.012
-1.283
Gng2
G protein subunit gamma 2
62.921
-53.461
Amphetamine addiction
Camk2a
Calcium/calmodulin-dependent protein kinase II alpha
2.111
-1.135
Arc
Activity-regulated cytoskeleton-associated protein
-2.096
3.674
Grin3a
Glutamate ionotropic receptor NMDA type subunit 3A
