A Study on the Immunohistochemical Expressions of Leptin and Leptin Receptor in Clear Cell Renal Cell Carcinoma

Figure 3

Leptin receptor overall and nuclear immunohistochemistry. (a) Negative control. (b) Positive liver control (cytoplasm positivity indicated by the red arrow; the nucleus remains unstained as indicated by the blue arrow). (c) Adjacent normal kidney (cytoplasm positivity indicated by the red arrow; the nucleus remains unstained as indicated by the blue arrow). (d) ccRCC (focal weak cytoplasmic positivity indicated by the red arrow, some of the ccRCC nucleus stained positive as indicated by the blue arrow). (e) Overall positive pixel. (f) Nuclear positive pixel. There was no differential overall and nuclear expression intensity of the leptin receptor in ccRCC compared with paired normal kidney.

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