Research Article
A Study on the Immunohistochemical Expressions of Leptin and Leptin Receptor in Clear Cell Renal Cell Carcinoma
Table 2
Expressions of leptin and leptin receptor in tumour tissue with correlation to cohort characteristics and tumour features.
| Variables | Leptin | Leptin receptor | Overall expression (%) (cytoplasm+membranous) | Nuclear expression (%) | Overall expression (%) (cytoplasm+membranous) | Nuclear expression (%) | Percentages | Low | High | value | Low | High | value | Low | High | value | Low | High | value |
| BMI | | | | | | | | | | | | | Normal | 10.0 | 16.7 | 0.097 | 20.0 | 13.3 | 0.384 | 18.3 | 11.7 | 0.760 | 21.7 | 18.3 | 0.426 | Obese | 26.7 | 15.0 | 25.0 | 28.3 | 21.7 | 16.7 | 20.0 | 26.7 | T stage | | | | | | | | | | | | | 1 | 20.0 | 16.7 | 0.342 | 18.3 | 25.0 | 0.414 | 15.0 | 13.3 | 0.212 | 21.7 | 18.3 | 0.414 | 2 | 11.7 | 3.3 | 15.0 | 5.0 | 8.3 | 8.3 | 8.3 | 11.7 | 3 | 5.0 | 11.7 | 10.0 | 11.7 | 15.0 | 6.7 | 11.7 | 13.3 | 4 | 0.0 | 0.0 | 1.7 | 0.0 | 1.7 | 0.0 | 0.0 | 1.7 | N stage | | | | | | | | | | | | | N0 | 33.3 | 26.7 | 0.523 | 41.7 | 33.3 | 0.084 | 38.3 | 25.0 | 0.374 | 36.7 | 36.7 | 0.483 | N1 | 3.3 | 5.0 | 3.3 | 8.3 | 1.7 | 3.3 | 5.0 | 8.3 | Metastasis | | | | | | | | | | | | | M0 | 30.0 | 28.3 | 0.587 | 33.3 | 33.3 | 0.582 | 28.3 | 20.0 | 0.814 | 35.0 | 36.7 | 0.836 | M1 | 6.7 | 3.3 | 11.7 | 8.3 | 11.7 | 8.3 | 6.7 | 8.3 | Clinical stage | | | | | | | | | | | | | I | 18.3 | 11.7 | 0.242 | 16.7 | 18.3 | 0.683 | 13.3 | 6.7 | 0.859 | 20.0 | 13.3 | 0.420 | II | 11.7 | 6.7 | 15.0 | 5.0 | 8.3 | 10.0 | 8.3 | 13.3 | III | 3.3 | 10.0 | 5.0 | 8.3 | 10.0 | 3.3 | 6.7 | 11.7 | IV | 3.3 | 3.3 | 8.3 | 10.0 | 8.3 | 8.3 | 6.7 | 6.7 | Grade | | | | | | | | | | | | | Grades 1-2 | 28.3 | 18.3 | 0.188 | 28.3 | 30.0 | 0.496 | 26.7 | 18.3 | 0.912 | 26.7 | 28.3 | 0.922 | Grades 3-4 | 8.3 | 13.3 | 16.7 | 11.7 | 13.3 | 10.0 | 15.0 | 16.7 |
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