Identification and Validation of an Energy Metabolism-Related lncRNA-mRNA Signature for Lower-Grade Glioma

Table 1

Function enrichment.

Category	Term	value	Genes
Biology process	GO:0006661~phosphatidylinositol biosynthetic process		INPP5J, ARF3, SYNJ1, PI4KA, PIP4K2A, MTMR7
	GO:0030203~glycosaminoglycan metabolic process		B3GAT1, GPC2, CHST9, BCAN, VCAN
	GO:0030206~chondroitin sulfate biosynthetic process		CHSY3, CHST9, BCAN, VCAN
	GO:0009725~response to hormone		ME1, OXCT1, FHL2, DHCR24
	GO:0035338~long-chain fatty-acyl-CoA biosynthetic process		ACOT7, ELOVL4, SLC25A1, ACOT4
	GO:0030208~dermatan sulfate biosynthetic process		UST, BCAN, VCAN
	GO:0055114~oxidation-reduction process		ME1, TYRP1, CYP46A1, CYP2C8, QDPR, CBR4, SRD5A1, CRYM, DHCR24
	GO:0006699~bile acid biosynthetic process		CYP46A1, STAR, SLC27A2
	GO:0046856~phosphatidylinositol dephosphorylation		INPP5J, SYNJ1, MTMR7
	GO:0008652~cellular amino acid biosynthetic process		GLS2, ASPA, GOT1
	GO:0042493~response to drug		STAR, BCHE, OXCT1, FABP3, SRD5A1, AACS
	GO:0019083~viral transcription		RPLP0, NUP93, TPR, RPS21
	GO:0006486~protein glycosylation		B3GAT1, B3GALT2, B4GALT6, LRP2
	GO:0070859~positive regulation of bile acid biosynthetic process		NR1D1, STAR
	GO:0006024~glycosaminoglycan biosynthetic process		GPC2, HAS1, HS3ST2
	GO:0006094~gluconeogenesis		GOT1, ENO2, SLC25A1
	GO:0006533~aspartate catabolic process		ASPA, GOT1
	GO:0071320~cellular response to cAMP		STAR, RPLP0, SRD5A1
	GO:0016101~diterpenoid metabolic process		STAR, SRD5A1
	GO:0071394~cellular response to testosterone stimulus		SRD5A1, AACS
	GO:0006629~lipid metabolic process		CPNE6, AACS, LRP2, FABP6
	GO:0060992~response to fungicide		STAR, SRD5A1
	GO:0044539~long-chain fatty acid import		FABP3, SLC27A2
	GO:0044321~response to leptin		NR1D1, STAR
	GO:0046951~ketone body biosynthetic process		HMGCLL1, AACS
	GO:0007584~response to nutrient		STAR, OXCT1, AACS
	GO:0035457~cellular response to interferon-alpha		STAR, TPR
	GO:0032869~cellular response to insulin stimulus		GOT1, STAR, SRD5A1
	GO:0046855~inositol phosphate dephosphorylation		SYNJ1, MTMR7
	GO:0046488~phosphatidylinositol metabolic process		PITPNM3, SYNJ1
	GO:0051292~nuclear pore complex assembly		NUP93, TPR
	GO:0071872~cellular response to epinephrine stimulus		STAR, SRD5A1
KEGG pathway	hsa01100:metabolic pathways		ME1, PLD3, TYRP1, HMGCLL1, B3GALT2, CYP2C8, SYNJ1, PI4KA, QDPR, HK1, AGMAT, RIMKLA, ACOT4, GLS2, ASPA, CKMT1A, GOT1, CHSY3, INPP5J, ENO2, B4GALT6, MTMR7, DHCR24
	hsa00562:inositol phosphate metabolism		INPP5J, SYNJ1, PI4KA, PIP4K2A, MTMR7
	hsa00250:alanine, aspartate, and glutamate metabolism		GLS2, ASPA, GOT1, RIMKLA
	hsa04070:phosphatidylinositol signaling system		INPP5J, SYNJ1, PI4KA, PIP4K2A, MTMR7
	hsa00330:arginine and proline metabolism		CKMT1A, GOT1, AGMAT, CARNS1
	hsa00062:fatty acid elongation		ACOT7, ELOVL4, ACOT4
	hsa00650:butanoate metabolism		HMGCLL1, OXCT1, AACS
	hsa00280:valine, leucine, and isoleucine degradation		HMGCLL1, OXCT1, AACS
	hsa01200:carbon metabolism		ME1, GOT1, ENO2, HK1