Research Article

[Retracted] Overexpression of 14-3-3σ Modulates Cholangiocarcinoma Cell Survival by PI3K/Akt Signaling

Table 2

Clinical and histopathological characteristics according to 14-3-3σ status in 65 extrahepatic cholangiocarcinomas.

14-3-3σ expression value
Total ()Negative ()Positive ()

Gender (%)
 Male37 (56.9)5 (55.6)32 (57.1)NS
 Female28 (43.1)4 (34.4)24 (42.9)
Age (%)
 ≥65 years22 (33.8)4 (34.4)18 (32.1)NS
 <65 years43 (66.2)5 (55.6)38 (67.9)
Tumor size (%)
 >2.5 cm45 (69.2)3 (33.3)42 (75.0)0.020
 ≤2.5 cm20 (30.8)6 (66.7)14 (25.0)
Pathologic differentiation (%)
 Well30 (46.2)2 (22.2)28 (50.0)NS
 Moderate29 (44.6)4 (44.4)25 (44.6)
 Poor6 (9.2)3 (33.4)3 (5.4)
Lymphatic permeation (%)
 No27 (41.5)7 (77.8)20 (35.7)0.027
 Yes38 (58.5)2 (22.2)36 (64.3)
Tumor stage (%)
 I+II25 (38.5)8 (66.7)17 (32.1)0.001
 III+IV40 (61.5)1 (33.3)39 (67.9)