Cerebrospinal Fluid Cytokines in Patients with Neurosyphilis: The Significance of Interleukin-10 for the Disease

Table 1

Clinical characteristics of patients with ANS, SNS, and NNS.

Clinical characteristics	NS ()		NNS ()
	SNS ()	ANS ()
Sex ratio () (M/F)	20/7	12/6	5/7
Age (years)
Serum RPR titer	1 : 16 (1 : 4-1 : 32)	1:8 (1 : 8-1 : 16)	1 : 2 (1 : 1-1 : 8)
Positive CSF RPR ()	22/27 (81.5%)^a	5/18 (27.8%)	0/12 (0%)
Positive CSF TPPA ()	27/27 (100%)	18/18 (100%)	0/12 (0%)
Positive CSF FTA-ABS ()	27/27 (100%)	18/18 (100%)	0/12 (0%)
CSF WBC count (/μL)	8.00 (5.00-15.00)	6.50 (3.75-14.00)	2.50 (1.25-3.00)
CSF protein level (mg/dL)	48.30 (33.70-84.50)	40.25 (31.28-55.90)	22.25 (17.90-32.42)

Values are expressed as median (IQR), unless otherwise indicated. NS: neurosyphilis; ANS: asymptomatic neurosyphilis; SNS: symptomatic neurosyphilis; NNS: nonneurosyphilis; M: male; F: female; RPR: rapid plasma reagin; CSF: cerebrospinal fluid; TPPA: pallidum particle agglutination; FTA-ABS: fluorescent treponemal antibody absorption. WBC: : white blood cell. ^a compared with ANS.