Research Article

Potential Anticancer Activity of Crude Ethanol, Ethyl Acetate, and Water Extracts of Ephedra foeminea on Human Osteosarcoma U2OS Cell Viability and Migration

Figure 8

Depicted effect of E. foeminea extracts on U2OS gene expression. E. foeminea downregulated the steady-state mRNA expression of markers involved in cell proliferation, migration, and apoptosis. By downregulating the steady-state mRNA expression of both B-catenin and p53, downstream markers of cell proliferation, migration, and apoptosis are, respectively, downregulated.