Research Article

Biological Pathways of Long-Term Visit-to-Visit Blood Pressure Variability in the American Population: Cardiovascular Health Study and Women’s Health Initiatives

Table 1

Characteristics of the study participants.

Categorical variables N (%)CHS (EA) N = 1,056Garnet (EA) N = 2,282Whims (EA) N = 3,316CHS (AA) N = 208Share (AA) N = 3,291

GWAS platform
Affymetrix 6.0Illumina humanomni1-quad v1-0BHumanOmniExpress Exome-8v1BAffymetrix 6.0
Sex
 Male385 (36.46)50 (24.04)
 Female671 (63.54)2,282 (100.00)3,316 (100.00)158 (75.96)3,291 (100.00)
Race
 European Americans1,056 (100.00)2,282 (100.00)3,316 (100.00)
 African Americans208 (100.00)3,291 (100.00)
Diabetes
 Yes673 (63.73)886 (38.83)512 (15.44)87 (41.83)1,158 (35.19)
 No383 (36.27)1,396 (61.17)2,804 (84.56)121 (58.17)2,133 (64.81)
Hyperlipidemia
 Yes61 (5.78)837 (36.68)1,293 (38.99)14 (6.73)1,356 (41.21)
 No995 (94.22)1,445 (63.32)2,023 (61.01)194 (93.27)1,935 (58.80)
Smoking
 Yes585 (55.40)170 (7.45)220 (6.63)180 (86.54)367 (11.15)
 No471 (44.60)2,112 (92.55)3,096 (93.37)28 (13.46)2,924 (88.85)
Antihypertensive medication
 Yes1,044 (98.86)2,281 (99.96)3,314 (99.94)205 (98.56)3,291 (100.00)
 No12 (1.14)1 (0.04)2 (0.06)3 (1.44)
Age72.42 (5.14)65.53 (6.69)68.54 (5.48)72.27 (5.06)61.24 (6.64)
Average systolic blood pressure139.94 (16.36)130.85 (11.22)132.59 (11.54)143.01 (16.21)132.48 (11.74)
Average diastolic blood pressure71.44 (8.58)73.35 (6.81)73.43 (6.79)74.47 (8.22)76.57 (7.00)