PCK1 Deficiency Shortens the Replicative Lifespan of Saccharomyces cerevisiae through Upregulation of PFK1

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Strain</td><td class="align_center">Genotype</td><td class="align_center">Source</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left" rowspan="2">BY4742</td><td class="align_center" rowspan="2">MATa his3Δ1 leu2Δ0 met15Δ0 ura3Δ0</td><td class="align_center">Gift from Dr.</td></tr><tr><td class="align_center">Matt Kaeberlein</td></tr><tr><td class="align_left">pck1Δ</td><td class="align_center">BY4742 pck1:URA3</td><td class="align_center">This study</td></tr><tr><td class="align_left">PCK1 OE</td><td class="align_center">BY4742 PCK1 OE:URA3</td><td class="align_center">This study</td></tr><tr><td class="align_left">pck1Δpfk1Δ</td><td class="align_center">BY4742 pfk1:URA3 pck1:LEU2</td><td class="align_center">This study</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Yeast strains used in this study.</div>

BioMed Research International

tab1

Table 1

Table 1: PCK1 Deficiency Shortens the Replicative Lifespan of Saccharomyces cerevisiae through Upregulation of PFK1