Spleen Stiffness Predicts Survival after Transjugular Intrahepatic Portosystemic Shunt in Cirrhotic Patients

Table 2

Univariate and multivariate analyses for predicting factors associated with survival after TIPS.

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Age (yr)	1.040 (1.002-1.080)	0.041	1.096 (1.044-1.150)	<0.001
Sex (male)	0.704 (0.301-1.646)	0.418
CTP^1 score	1.488 (1.078-2.054)	0.016
MELD^2 score	1.252 (1.075-1.459)	0.004
SB^3 (μmol/L)	1.028 (1.005-1.050)	0.015
PLT^4 (×10^12/L)	0.994 (0.980-1.007)	0.346
ALT^5 (IU/L)	1.011 (0.996-1.027)	0.157
AST^6 (IU/L)	1.011 (0.997-1.025)	0.113
ALB^7 (g/L)	0.984 (0.888-1.090)	0.754
Cr^8 (μmol/L)	1.011 (1.000-1.023)	0.045
PVT^9	1.387 (0.413-4.657)	0.597
Ascites	1.727 (1.149-2.596)	0.009
Diameter of shunt	2.479 (1.204-5.102)	0.014	3.450 (1.684-7.068)	0.001
Liver stiffness (m/s)	4.575 (1.667-12.560)	0.005	5.038 (1.530-16.585)	0.008
Spleen stiffness (m/s)	29.273 (6.211-137.976)	<0.001	57.440 (10.025-329.115)	<0.001

¹CTP: Child-Turcotte-Pugh; ²MELD: model for end-stage liver disease; ³SB: serum bilirubin; ⁴PLT: platelet; ⁵ALT: alanine aminotransferase; ⁶AST: aspartate aminotransferase; ⁷ALB: albumin; ⁸Cr: creatinine; ⁹PVT: portal vein thrombosis.