Research Article
Systematic Characterization of Prognostic Values of Peroxiredoxin Family in Gastric Cancer
Table 2
Association between PRDX expression and OS in GC patients with different Lauren classifications.
| PRDXs | Lauren classification | Cases | Low | High | HR (95% CI) | value |
| PRDX1 | Intestinal | 320 | 160 | 160 | 0.56 (0.41–0.78) | <0.001 | Diffuse | 241 | 120 | 121 | 0.59 (0.42–0.84) | 0.003 | Mixed | 32 | 16 | 16 | 0.75 (0.27–2.06) | 0.571 |
| PRDX2 | Intestinal | 320 | 160 | 160 | 0.47 (0.34–0.65) | <0.001 | Diffuse | 241 | 120 | 121 | 0.99 (0.70–1.39) | 0.949 | Mixed | 32 | 16 | 16 | 1.24 (0.44–3.52) | 0.680 |
| PRDX3 | Intestinal | 320 | 160 | 160 | 0.59 (0.43–0.81) | <0.001 | Diffuse | 241 | 120 | 121 | 0.66 (0.47–0.93) | 0.017 | Mixed | 32 | 16 | 16 | 0.53 (0.19–1.50) | 0.222 |
| PRDX4 | Intestinal | 320 | 160 | 160 | 0.76 (0.55–1.04) | 0.088 | Diffuse | 241 | 120 | 121 | 0.72 (0.51–1.01) | 0.054 | Mixed | 32 | 16 | 16 | 0.51 (0.18–1.44) | 0.197 |
| PRDX5 | Intestinal | 269 | 134 | 135 | 0.92 (0.64–1.32) | 0.640 | Diffuse | 240 | 120 | 120 | 0.85 (0.61–1.20) | 0.360 | Mixed | 29 | 14 | 15 | 1.22 (0.41–3.65) | 0.721 |
| PRDX6 | Intestinal | 320 | 160 | 160 | 0.67 (0.49–0.92) | 0.012 | Diffuse | 241 | 120 | 121 | 0.86 (0.61–1.21) | 0.384 | Mixed | 32 | 16 | 16 | 1.51 (0.54–4.26) | 0.429 |
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