Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection

Figure 7

Immunohistochemical detection of collagen type I in the lamina propria (LP) and submucosa (SM) from tracheal tissue, in which severe expression is observed as strong red immunostaining in (b) group I (control) and (f) group V (mitomycin C), as well as moderate expression as light red in the animals of (c) group II (hyaluronic acid), (d) group III (collagen-PVP), and (e) group IV (mixture of hyaluronic acid+collagen-PVP). (a) Presurgery samples. (g) Tracheal tissue as a negative control. (h) The human placenta was the positive control.

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