Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection

Table 1

Expression in pixels of the different ECM proteins in all study groups prior to surgery and at the end of the study. Values are expressed as the of pixels quantified in the entire sample circumference. Group I = control; group II = hyaluronic acid; group III = collagen-PVP; group IV = mixture of hyaluronic acid+collagen-PVP; group V = mitomycin C.

Study groups	Decorin	MMP1	MMP9
Presurgery
Group I (control)
Group II (hyaluronic acid)
Group III (collagen-PVP)
Group IV (hyaluronic acid+collagen-PVP)
Group V (mitomycin C)

Expression based on pixel analysis of decorin, MMP1, and MMP9 postresection and end-to-end anastomosis of trachea, presurgery, and after treatment with different wound healing modulators. . : ANOVA, Dunnett, and Tukey. Groups III and IV vs. presurgery and groups I and V. : ANOVA, Dunnett, and Tukey. Group V vs. presurgery and groups II and III.