SOX1 and PAX1 Are Hypermethylated in Cervical Adenocarcinoma and Associated with Better Prognosis

Figure 1

SOX1 and PAX1 methylation levels in cervical adenocarcinoma. (a) Methylation-Index (M-Index) of SOX1 and PAX1 methylation between the noncancer group (30 noncancer tissues) and cervical cancer group (175 adenocarcinoma), ; (b) the area under the ROC curve for the SOX1 and PAX1 methylation assay was calculated for exploring cervical cancer. The sensitivity and specificity of SOX1 methylation were 87.22% and 56.67%, respectively, with a cut-off point of . The AUC was 88.42%. And the sensitivity and specificity of PAX1 methylation were 40.30% and 100%, separately, with a cut-off point of . The AUC was 70.80%.

(a)

(b)