Research Article
SOX1 and PAX1 Are Hypermethylated in Cervical Adenocarcinoma and Associated with Better Prognosis
Table 2
Association between SOX1m or PAX1m and clinicopathological characteristics in 175 CAC patients.
| Variable | Number of patients | SOX1m | PAX1m | () | Positive | Negative | value | Positive | Negative | value |
| Age (years) | | | | 0.625 | | | 0.91 | <50 | 96 (54.86%) | 83 | 13 | | 28 | 68 | | ≥50 | 79 (45.14%) | 70 | 9 | | | | | FIGO stage | | | | 0.937 | | | 0.766 | <IIB | 127 (71.57%) | 112 | 15 | | 36 | 91 | | ≥IIB | 48 (27.43%) | 41 | 6 | | 14 | 33 | | Tumor size | | | | 0.748 | | | 0.412 | <4 | 101 (57.71%) | 89 | 12 | | 27 | 74 | | ≥4 | 72 (41.14%) | 62 | 10 | | 23 | 49 | | Deep of invasion | | | | 0.929 | | | 0.863 | <1/2 | 74 (42.29%) | 64 | 10 | | 21 | 53 | | ≥1/2 | 90 (51.43%) | 78 | 12 | | 24 | 66 | | LNM | | | | 0.418 | | | 0.17 | No | 126 (72%) | 111 | 15 | | 37 | 89 | | Yes | 41 (23.43%) | 34 | 7 | | 8 | 33 | | Histologic grade | | | | 0.644 | | | 0.146 | Well/moderate | 119 (68%) | 104 | 15 | | 33 | 86 | | Poor | 45 (25.71%) | 38 | 7 | | 17 | 28 | |
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