Protective Effect of Methylxanthine Fractions Isolated from Bancha Tea Leaves against Doxorubicin-Induced Cardio- and Nephrotoxicities in Rats

Figure 6

Photomicrographs of renal cortex stained with H&E ×400. (a) Control; normal structure of nephrons. (b) Doxorubicin-treated group (cumulative dose: 20 mg/kg); damaged tubular cells (arrow left) and total collapse of glomeruli (arrow right). (c, d) Groups pretreated with MXB 5 mg/kg and 1 mg/kg; the both groups show less damage of kidney tissue. The lesions are mainly in the cortical area.

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