Research Article

Circular RNA hsa_circ_0000467 Promotes the Development of Gastric Cancer by Competitively Binding to MicroRNA miR-326-3p

Figure 3

Hsa_circ_0000467 has binding sites with miR-326-3p. (a) Differential miRNA expression in gastric cancer cells in which hsa_circ_0000467 was decreased was detected by qRT-PCR. (b) Schematic model showing the putative binding sites for miR-326-3p and hsa_circ_0000467. (c) Construction of dual-luciferase reporter plasmids containing the WT or Mut hsa_circ_0000467 sequence. (d) The luciferase activities of the blank controls or miR-326-3p mimics and the WT or Mut hsa_circ_0000467 cotransfected BGC-823 cells were determined by luciferase reporter assays. ns: not significant, , .
(a)
(b)
(c)
(d)