Research Article
Circular RNA hsa_circ_0000467 Promotes the Development of Gastric Cancer by Competitively Binding to MicroRNA miR-326-3p
Table 3
Correlation between hsa_circ_0000467 expression and clinicopathological features of gastric cancer.
| Clinicopathological features | Patients (n = 30) | hsa_circ_0000467 expressiona | value | High group | Low group |
| Gender | | | | 0.6903 | Male | 21 | 10 (33.3%) | 11 (36.7%) | | Female | 9 | 5 (16.7%) | 4 (13.3%) | | Age (year) | | | | 0.6660 | ≥70 | 7 | 4 (13.3%) | 3 (10.0%) | | <70 | 23 | 11 (36.7%) | 12 (40.0%) | | Tumor size (cm) | | | | 0.7125 | ≥5 | 13 | 7 (23.3%) | 6 (20.0%) | | <5 | 7 | 8 (26.7%) | 9 (30.0%) | | Histological grade | | | | 0.0224 | Well | 3 | 0 (0.0%) | 3 (10.0%) | | Moderately | 12 | 4 (13.3%) | 8 (26.7%) | | Poor | 15 | 11 (36.7%) | 4 (13.3%) | | TNM stage | | | | 0.1953 | I and II | 7 | 2 (6.7%) | 5 (16.7%) | | III and IV | 23 | 13 (43.3%) | 10 (33.3%) | | Pathological T category | | | | 0.0674 | T1 | 0 | 0 (0.0%) | 0 (0.0%) | | T2 | 1 | 0 (0.0%) | 1 (3.3%) | | T3 | 24 | 10 (33.3%) | 14 (46.7%) | | T4 | 5 | 4 (13.3%) | 1 (3.3%) | | Lymphatic node metastasis | | | | 0.9720 | N0 | 7 | 3 (10.0%) | 4 (13.3%) | | N1 | 2 | 1 (3.3%) | 1 (3.3%) | | N2 | 11 | 6 (20.0%) | 5 (16.7%) | | N3 | 10 | 5 (16.7%) | 5 (16.7%) | |
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TNM: tumor node metastasis. Significant difference: . aUsing median hsa_circ_0000467 values as cutoff. |