Chitosan-Based Delivery of Avian Reovirus Fusogenic Protein p10 Gene: In Vitro and In Vivo Studies towards a New Vaccine against Melanoma

<div>Effect of NP-ARV treatment on tumor-infiltrated and splenic T cells. (a) Representative dot plots of the intratumoral T CD8+ and T CD4+ lymphocytes are shown for the nontreated animals (control), chitosan alone (CH), and NP-ARV-treated group. (b) Graph bar of the percentage of each population in tumor CD45+ cells. (c) Representative dot plots of the splenic T CD8+ and T CD4+ lymphocytes for the nontreated animals (control), chitosan alone (CH), and NP-ARV-treated group. (d) Graph bar of the percentage of each population in splenic CD45+ cells. 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BioMed Research International

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Figure 4

Figure 4: Chitosan-Based Delivery of Avian Reovirus Fusogenic Protein p10 Gene: In Vitro and In Vivo Studies towards a New Vaccine against Melanoma