Research Article

Coexpression Network Analysis Identifies a Novel Nine-RNA Signature to Improve Prognostic Prediction for Prostate Cancer Patients

Table 4

Function enrichment analysis.

CategoryTermCount valueGenes

GO_BPGO:0007204~positive regulation of cytosolic calcium ion concentration84.15E-04PTGER1, PTGER2, CYSLTR1, GALR2, GJA1, CD52, FPR3, and CXCR3
GO_BPGO:0010818~T cell chemotaxis32.71E-03GPR183, CXCR3, and CXCL10
GO_BPGO:0016525~negative regulation of angiogenesis53.51E-03SERPINF1, FASLG, CXCR3, SPARC, and CXCL10
GO_BPGO:0032496~response to lipopolysaccharide76.37E-03PTGER1, PTGER2, KCNJ8, ELANE, FASLG, SPARC, and CXCL10
GO_BPGO:0006935~chemotaxis67.84E-03RARRES2, CYSLTR1, CXCR3, CCL5, DEFB1, and CXCL10
GO_BPGO:0006954~inflammatory response101.47E-02TUSC2, PTGER1, PTGER2, RARRES2, NMI, FPR3, CXCR3, CCL5, CXCL10, and AOC3
GO_BPGO:0039702~viral budding via host ESCRT complex32.04E-02CHMP2A, VPS37B, and VPS37D
GO_BPGO:0016197~endosomal transport42.89E-02CHMP2A, VPS37B, VPS37D, and RAB13
GO_BPGO:0001937~negative regulation of endothelial cell proliferation33.42E-02GJA1, CXCR3, and SPARC
GO_BPGO:0060333~interferon-gamma-mediated signaling pathway43.48E-02NMI, HLA-DPB1, HLA-E, and GBP1
GO_BPGO:0019058~viral life cycle33.87E-02CHMP2A, VPS37B, and VPS37D
GO_BPGO:0036258~multivesicular body assembly33.87E-02CHMP2A, VPS37B, and VPS37D
GO_BPGO:0015031~protein transport94.67E-02CHMP2A, COPZ2, DNAJC15, GOLT1A, EIF5AL1, KIF18A, VPS37B, VPS37D, and NACA2
GO_BPGO:0000727~double-strand break repair via break-induced replication24.93E-02GINS2, CDC45
KEGGhsa04080:Neuroactive ligand-receptor interaction71.10E-02PTGER1, PTGER2, GLRB, CYSLTR1, ADORA2B, GALR2, and FPR3
KEGGhsa04110:Cell cycle42.16E-02E2F2, CDC45, TTK, and ORC6
KEGGhsa04623:Cytosolic DNA-sensing pathway32.21E-02POLR2L, CCL5, and CXCL10
KEGGhsa00190:Oxidative phosphorylation2.511.10E-02UQCRC1, COX7A1, NDUFB7, and NDUFB9
KEGGhsa04060:Cytokine-cytokine receptor interaction53.86E-02OSM, FASLG, CXCR3, CCL5, and CXCL10
KEGGhsa04020:Calcium signaling pathway44.43E-02PTGER1, CYSLTR1, ADORA2B, and CACNA1H

GO: Gene Ontology; BP: biological process; KEGG: Kyoto Encyclopedia of Genes and Genomes.