Pathway Maps of Orphan and Complex Diseases Using an Integrative Computational Approach

Table 1

Simple parameters of both networks determined using the network analyzer Cytoscape plugin.

	CDs-gene association network	ODs-gene association network
Number of nodes	40,461	7,748
Number of edges	516,883	7,418
Clustering coefficient	0	0
Connected components	60	1,492
Network diameter	10	34
Shortest paths	1,627,436,746	13,223,970
Characteristic path length	3.717	10.169
Avg. number of neighbors	25.534	1.915
Network density	0.001	0
Network heterogeneity	3.852	1.400