Molecular Epidemiology and Clinical Features Analysis of Respiratory Adenovirus Infections Reveals Correlations between Genotype, Inflammatory Biomarkers, and Disease Severity

Table 3

Performance of biomarkers for distinguishing severe HAdV infection from nonsevere infection.

	AUC	CI 95%		Optimal cutoff value	Sensitivity	Specificity	Positive likelihood ratio	Negative likelihood ratio	Youden index
PCT	0.822	0.729-0.915	< 0.001	0.755	88.90%	70.60%	3.02	0.157	0.595
CRP	0.647	0.521-0.774	0.033	18.05	77.80%	50.90%	1.59	0.436	0.287
WBC	0.572	0.434-0.710	0.286	5.945	32.10%	91.00%	3.6	0.745	0.232

AUC: area under the curve; CI: confidence interval; WBC: whole blood cell; CRP: C-reactive protein; PCT: procalcitonin.