Molecular Epidemiology and Clinical Features Analysis of Respiratory Adenovirus Infections Reveals Correlations between Genotype, Inflammatory Biomarkers, and Disease Severity

Table 4

Performance of biomarkers for distinguishing HAdV-7 from HAdV-3 infection.

	AUC	CI 95%		Optimal cutoff value	Sensitivity	Specificity	Positive likelihood ratio	Negative likelihood ratio	Youden index
PCT	0.773	0.661-0.886	< 0.001	0.755	72.20%	75.00%	2.89	0.37	0.472
CRP	0.52	0.382-0.659	0.773	14.35	69.40%	40.60%	1.17	0.75	0.1
WBC	0.739	0.624-0.853	< 0.001	11.34	75.70%	69.40%	2.48	0.35	0.451

AUC: area under the curve; CI: confidence interval; WBC: whole blood cell; CRP: C-reactive protein; PCT: procalcitonin.