Research Article

Miscarriage on Endometriosis and Adenomyosis in Women by Assisted Reproductive Technology or with Spontaneous Conception: A Systematic Review and Meta-Analysis

Table 1

Characteristics of identified literature.

Authors (year)Study designSample sizeStudy locationMode of conceptionType of diseaseExposure ascertainmentOutcomes

Porpora et al. (2020)Prospective cohort study425ItalySCEMSSurgical/clinical/instrumental diagnosisMiscarriage, PPH, IUGR, gestational diabetes, stillbirth, low birthweight preterm birth, placenta praevia, placental abruption, preeclampsia
Farland et al. (2019)Prospective cohort study196722AmericaSCEMSLaparoscopic diagnosisMiscarriage, gestational diabetes, ectopic pregnancy, stillbirth, low birthweight, preterm birth
Mekaru et al. (2014)Retrospective cohort study108JapanSCEMSLaparoscopic evaluationMiscarriage, low birthweight, preterm birth
Pittaway et al. (1988)Retrospective cohort study350AmericaSCEMSLaparoscopy or laparotomyMiscarriage, ectopic pregnancy
Hjordt Hansen et al. (2014)Retrospective cohort study123335DenmarkSCEMSDischarge diagnosis by the international classification of diseasesMiscarriage, ectopic pregnancy
Santulli et al. (2016)Retrospective cohort study1851FranceSCEMSSurgical examination of the abdominopelvic cavityMiscarriage
Saraswat et al. (2016)Retrospective cohort study13665ScotlandSCEMSLaparoscopy or laparotomyMiscarriage, PPH, APH, low birthweight, stillbirth, ectopic pregnancy, preterm birth, placenta praevia, placental abruption
Geber et al. (1995)Retrospective cohort study1506LondonIVFEMSLaparoscopyMiscarriage, ectopic pregnancy
Omland et al. (2005)Retrospective cohort study1026NorwayIVF/ICSIEMSLaparoscopic diagnosisMiscarriage, ectopic pregnancy, stillbirth
Kuroda et al. (2009)Case control study82JapanIVF/ICSIEMSLaparoscopic surgery/ultrasound/MRIMiscarriage
Olivennes et al. (1995)Retrospective cohort study325AmericaIVFEMSLaparoscopic evaluationMiscarriage
Polat et al. (2014)Retrospective cohort study616TurkeyIVFEMSLaparoscopy or laparotomy, transvaginal ultrasonographyMiscarriage
Guo et al. (2016)Retrospective cohort study437ChinaIVFEMSLaparoscopy or laparotomyMiscarriage
Pop et al. (2014)Prospective cohort study235SerbiaIVFEMSSurgically confirmedMiscarriage
Sharma et al. (2020)Prospective cohort study652IndiaIVFEMSLaparoscopic diagnosisMiscarriage, PPH, APH, gestational diabetes, preterm birth, IUGR, preeclampsia
Matalliotakis et al. (2007)Case control study174GreeceIVF-ETEMSLaparoscopic diagnosisMiscarriage
Curtis et al. (1993)Retrospective cohort study206EnglandIVF-ETEMSLaparoscopic diagnosisMiscarriage, ectopic pregnancy
Arici et al. (1996)Case control study105AmericaIVF-ETEMSLaparoscopic diagnosisMiscarriage
Bergendal et al. (1998)Retrospective cohort study146CanadaIVF-ETEMSLaparoscopic diagnosisMiscarriage, ectopic pregnancy
Pabuccu et al. (2004)Randomized controlled trials171TurkeyICSIEMSLaparoscopic diagnosisMiscarriage
Mathieud et al. (2010)Retrospective cohort study526FranceIVFEMSSonography, MRIMiscarriage
Kim et al. (2011)Prospective cohort study40KoreaIVF-ETEMSLaparoscopic diagnosisMiscarriage
Kuivasaari et al. (2005)Retrospective cohort study185FinlandIVF/ICSIEMSLaparoscopic diagnosisMiscarriage, ectopic pregnancy
Opoien et al. (2012)Retrospective cohort study2245NorwayICSIEMSLaparoscopic diagnosisMiscarriage
Singh et al. (2013)Case control study340IndiaIVFEMSLaparoscopic diagnosisMiscarriage
Senepati et al. (2016)Retrospective cohort study347185WashingtonIVFEMSLaparoscopic diagnosisMiscarriage
Vaz et al. (2017)Retrospective cohort study181BrazilIVFEMSLaparoscopy or MRIMiscarriage
Esinler et al. (2006)Case control study156TurkeyIVF/ICSIEMSLaparoscopic diagnosisMiscarriage
Bahceci et al. (2005)Retrospective cohort study1244TurkeyICSIEMSLaparoscopic diagnosisMiscarriage
Sharma et al. (2019)Retrospective cohort study973IndiaIVFEMS and ADEMS confirmed by laparoscopy, AD diagnosed by TVSMiscarriage, PPH, APH, preterm birth, IUGR, preeclampsia
Costello et al. (2011)Retrospective cohort study201AustraliaIVF/ICSIADTransvaginal ultrasoundMiscarriage
Youm et al. (2011)Case control study154KoreaIVF-ETADTVSMiscarriage
Thailluri et al. (2012)Retrospective cohort study213AustraliaIVF-ETADTVSMiscarriage
Benaglia et al. (2014)Case control study98ItalyIVF/ICSIADTVSMiscarriage
Hashimoto et al. (2017)Case control study294JapanARTADMRI/TVSMiscarriage
Martinez-Conejero et al. (2011)Retrospective cohort study443SpainARTADTVSMiscarriage
Yan et al. (2014)Retrospective cohort study154ChinaARTADTransvaginal ultrasoundMiscarriage, ectopic pregnancy
Salim et al. (2012)Prospective cohort study275LondonARTADTransvaginal ultrasoundMiscarriage
Schwartz et al. (2017)Cross-sectional study940SwitzerlandSC or ARTEMSSurgical diagnosisMiscarriage

SC: spontaneous conception; ART: assisted reproductive technology; IVF: in vitro fertilization; ICSI: intracytoplasmic sperm injection; EMS: endometriosis; AD: adenomyosis; TVS: transvaginal sonography; MRI: magnetic resonance imaging; APH: antepartum hemorrhage; PPH: postpartum hemorrhage; IUGR: intrauterine growth restriction.