Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?

Figure 3

Multiple sequence alignment among Sars-CoV-2 M protein variants and a set of most similar homologous proteins. The sequence label Sars-CoV-2 indicates the reference sequence identified by the RefSeq code YP_009724393. Red box indicates the variant sites at the N-terminal discussed in the text. Numbered red bars under the multiple alignment mark the prediction of transmembrane helices. The location of the connect loop with respect to the virion surface is indicated as “in” or “out”. Blu background denotes conserved alignment positions.