Ensemble Learning Prediction of Drug-Target Interactions Using GIST Descriptor Extracted from PSSM-Based Evolutionary Information

Table 4

5-fold cross-validation results were generated through the proposed method on the GPCR dataset.

Testing set	Accuracy (%)	Precision (%)	Sensitivity (%)	MCC (%)	AUC	AUPR
1	83.86	81.89	85.25	72.91	0.8853	0.7820
2	81.89	79.37	83.33	70.29	0.8894	0.7493
3	78.74	84.75	73.53	66.35	0.8660	0.8154
4	85.04	88.29	79.67	74.34	0.8998	0.8591
5	82.28	82.48	84.33	70.71	0.8992	0.7993
Average	82.36 ± 2.39	83.35 ± 3.36	81.22 ± 4.79	70.92 ± 3.04	0.8879 ± 0.0138	0.8010 ± 0.0407