The Establishment of Esophageal Precancerous Lesion Model by Using p53 Conditional Knockout Mouse in Esophageal Epithelium

Figure 3

NMBA-induced esophageal precancerous lesions in KO mice. (a) Classification of mouse esophageal (HE-stained) lesions at 16 weeks and the number of the lesions grade. (b) Classification of mouse esophageal (HE-stained) lesions at 48 weeks and the number of the lesions grade. (c) Total lesions of mouse esophageal tissues at 48 weeks: the esophageal lesions of the two groups were accumulated separately ( means ; scale bar, 100 μm).

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