Preclinical Development of Mahanine-Enriched Fraction from Indian Spice Murraya koenigii for the Management of Cancer: Efficacy, Temperature/pH stability, Pharmacokinetics, Acute and Chronic Toxicity (14-180 Days) Studies

Table 10

Serum biochemistry of the subacute toxicity study group of mice.

Test (units)	Control	Treated	Fold change
Urea (mg/dL)			1.03
BUN (mg/dL)			1.03
Creatinine (mg/dL)			1.1
ALT (U/L)			1.09
ALP (U/L)			0.94
GGT (U/L)			0.9
Bilirubin (mg/dL)			1.15
Total cholesterol (mg/dL)			1.16
Triglycerides (mg/dL)			1.2
SGOT (U/L)			0.78
Total protein (g/dL)			1.16
Albumin (ALB, g/dL)			1.23
Globulin (GLB, g/dL)			1.06
ALB : GLB			1.25
LDH (U/L)			0.88

Fold change (control/treated value) is the relative value where the control value is considered as 1.0 and the treated value is compared with it. Data indicate . There are no significant () differences between the control and treated mice in their biochemical parameters.