The PARK2 Mutation Associated with Parkinson’s Disease Enhances the Vulnerability of Peripheral Blood Lymphocytes to Paraquat

Table 1

Clinical features of sporadic patients.

Clinical feature	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5
Sex	Woman	Woman	Man	Man	Man
Age at disease onset (years)	34	31	33	30	36
Disease duration (years)	3	2	5	6	5
Bradykinesia	+	+	+	+	+
Rigidity	+	+	+	+	+
Resting tremor	—	—	+	+	—
Postural tremor	—	—	—	+	—
Shuffling gait	—	—	+	—	+
Postural instability	—	—	—	—	—
Hyperreflexia	—	—	—	—	—
Diurnal fluctuations	—	—	—	+	—
Foot dystonia	—	—	—	—	—
Hoehn and Yahr stage at last examination (off state)	1	1	2	2	2
UPDRS III score at last exam (off state)	13	17	22	24	20