Prognostic Role of MicroRNA 222 in Patients with Glioma: A Meta-analysis

Table 1

Characteristics of the included articles.

Author	Country	Sample	Number	Stage	Cut-off	Method	Results	HR (95% CI)	value	Quality score (NOS)
Chen Y	China	Tissue	114	IV	None	Q-PCR	OS	1.01 (0.65-1.58)	0.965	9
Zhang R	China	Blood	51	I-IV	None	Q-PCR	OS	2.81 (1.70-4.65)	0.0001	8
Li X	China	Tissue	45	I-IV	Mean	Q-PCR	OS	2.13 (1.01-4.48)	0.043	8
Zhang C	China	Tissue	36	I-IV	—	IHC	OS	2.39 (1.15-4.96)	0.02	8
Sun C	USA	Tissue	548	IV	Median	—	OS	1.68 (1.23-2.29)	0.001	8
Srinivasan S	USA	Tissue	111	IV	60%	—	OS	1.26 (1.11-1.43)	0.0004	7
Delfino K.R.	USA	Tissue	253	IV	—	—	OS	2.14 (1.51-3.03)	<0.0001	7
Zhao H	USA	Blood	106	IV	Median	—	DFS	1.71 (1.07-3.63)	0.038	7
Chen W	USA	Tissue	89	IV	Median	—	DFS	0.71 (0.46-1.09)	0.12	7
			102	IV	Median	—	DFS	1.11 (0.99-1.23)	0.07	7
			109	IV	Median	—	DFS	0.96 (0.86-1.08)	0.53	7

HR: hazard ratio; CI: confidence interval; Q-PCR: quantitative polymerase chain reaction; IHC: immunohistochemistry; NOS: Newcastle–Ottawa scale.