Histone Deacetylase Inhibition Attenuates Aortic Remodeling in Rats under Pressure Overload

<div>Effect of MGCD on the expression levels of angiotensin II receptors in rats after TAC. mRNA expression levels of angiotensin II type 1 receptor (<i>Agtr1</i>) and type 2 receptor (<i>Agtr2</i>) were determined by qRT-PCR. The TAC rats had higher <i>Agtr1</i> (a) and <i>Agtr2</i> (b) mRNA expression, which decreased with MGCD treatment. 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BioMed Research International

fig5

Figure 5

Figure 5: Histone Deacetylase Inhibition Attenuates Aortic Remodeling in Rats under Pressure Overload 