An UPLC-MS/MS Method for Simultaneous Quantification of the Components of Shenyanyihao Oral Solution in Rat Plasma

Table 5

Extraction recovery and matrix effect of the components in rat plasma sample.

Compounds	Concentration (ng/ml)	Extraction recovery (%)	RSD%	Matrix effect (%)	RSD%
Stachydrine	10.00		1.34		4.06
	250.00		1.22		6.15
	2000.00		2.61		1.92
Danshensu	2.00		0.81		8.54
	50.00		5.54		4.37
	400.00		1.22		0.25
Chlorogenic acid	0.20		4.16		8.75
	5.00		3.45		3.26
	40.00		0.52		0.29
Protocatechuic acid	0.20		2.09		3.61
	5.00		2.84		0.57
	40.00		0.32		1.92
Plantamajoside	0.10		1.00		7.36
	2.50		2.98		0.49
	20.00		1.83		2.00
Aesculetin	0.20		1.91		1.32
	5.00		2.22		1.02
	40.00		1.61		0.84
Isoquercitrin	0.20		4.78		3.20
	5.00		3.18		1.01
	40.00		0.71		0.76
Ferulic acid	2.00		5.88		4.02
	50.00		3.81		1.19
	400.00		0.71		0.42
Baicalin	10.00		3.20		5.02
	250.00		3.84		4.33
	2000.00		2.96		3.08
Baicalein	2.00		2.07		4.63
	50.00		4.72		1.68
	400.00		5.24		4.08