Enhancement of Antibacterial Activity of Paludifilum halophilum and Identification of N-(1-Carboxy-ethyl)-phthalamic Acid as the Main Bioactive Compound

Table 1

Activity spectrum of N-(1-carboxy-ethyl)-phthalamic acid and the positive control ampicillin against 6 types of cultures. The values in the table are representative of the range of MICs (μg/mL) determined in three independent experiments.

Organism(acquired resistance)	N-(1-carboxy-ethyl)-phthalamic acid	Ampicillin
Gram-negative bacteria
Salmonella enterica CIP	12.5–25	25
Escherichia coli ATCC 8739 (E, VA)	>200	12.5
Pseudomonas aeruginosa ATCC 9027	12.5–25	12.5
Gram-positive bacteria
Staphylococcus aureus ATCC 6538	25–50	25
Listeria ivanovii BUG 496	>100	25
Micrococcus luteus LB 14110	>100	25