miR-654-5p Targets HAX-1 to Regulate the Malignancy Behaviors of Colorectal Cancer Cells

Figure 2

miR-654-5p targets HAX-1 in CRC. (a) Putative binding region between miR-654-5p and the 3′-UTR of HAX-1. (b) Relative luciferase activity was measured in CRC cells carrying luciferase reporter constructs or synthetic miRNAs. (c) HAX-1 expression in CRC cells carrying miR-654-5p mimic or miR-con. miR-654-5p: microRNA-654-5p; CRC: colorectal cancer; miR-con: control miRNA; wt: wild-type; mt: mutant; HAX-1: hematopoietic cell-specific protein 1-associated protein X-1.

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