Clinical Study
Effect of Hydrocortisone on Intradialytic Hypotension: A Preliminary Investigational Study
(a) Frequency of IDH episodes with and without the intervention for each patient |
| | Day 1 | Day 2 | Day 3 | Day 1+HC | Day 2+HC | Day 3+HC |
| Patient 1 | Y | Y | Y | N | N | N | Patient 2 | Y | N | N | Y | Y | N | Patient 3 | Y | Y | Y | N | N | N | Patient 4 | Y | Y | N | N | N | N | Patient 5 | Y | N | Y | N | Y | Y | Patient 6 | Y | N | Y | N | N | N | Patient 7 | Y | Y | Y | Y | N | Y | Patient 8 | Y | Y | Y | N | Y | Y | Patient 9 | Y | Y | Y | Y | N | Y | Patient 10 | N | Y | N | N | N | N | Patient 11 | Y | Y | N | N | N | N | Patient 12 | N | Y | Y | N | N | N | Patient 13 | Y | N | Y | N | N | N | Patient 14 | Y | Y | N | N | N | N | Total | 12 | 10 | 9 | 3 | 3 | 4 |
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IDH: intradialytic hypotension; HC: hydrocortisone; Y: yes; N: no.
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(b) The characteristics of every patient listed in (a) |
| | Age (year) | Sex | DM | HTN | Weight (kilogram) | Interdialytic fluid gain (liter) | TSH (mIU/l) | Morning cortisol (nmol/l) | ACTH stimulation test | Adrenal insufficiency |
| Patient 1 | 37 | M | N | N | 53.5 | 4.2 | 1.8 | 311 | Not indicated | N | Patient 2 | 51 | F | Y | Y | 95.5 | 3.5 | 2.8 | 45 | Normal | N | Patient 3 | 60 | F | Y | Y | 95.0 | 4.0 | 4.2 | 419 | Not indicated | N | Patient 4 | 70 | F | Y | Y | 85.0 | 3.5 | 4.3 | 202 | Normal | N | Patient 5 | 45 | F | N | N | 65.0 | 3.3 | 0.8 | 319 | Not indicated | N | Patient 6 | 63 | F | Y | Y | 73.0 | 3.3 | 1.9 | 555 | Not indicated | N | Patient 7 | 51 | F | N | Y | 95.0 | 3.0 | 1.1 | 287 | Not indicated | N | Patient 8 | 63 | M | Y | Y | 87.0 | 5.3 | 2.3 | 107 | Normal | N | Patient 9 | 49 | M | N | N | 49.0 | 3.7 | 2.5 | 94 | Abnormal | Y | Patient 10 | 45 | F | N | N | 49.0 | 1.0 | 1.5 | 199 | Normal | N | Patient 11 | 38 | F | N | N | 60.0 | 4.5 | 8.6 | 417 | Not indicated | N | Patient 12 | 65 | F | Y | Y | 93.0 | 3.5 | 2.2 | 493 | Not indicated | N | Patient 13 | 52 | M | Y | N | 72.0 | 4.0 | 2.8 | 169 | Abnormal | Y | Patient 14 | 61 | M | N | Y | 90.0 | 3.0 | 0.5 | 263 | Abnormal | Y |
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DM: diabetes mellitus; HTN: hypertension; TSH: thyroid-stimulating hormone; M: male; F: female; Y: yes; N: no.
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