Preoperative Systemic Immune-Inflammation Index (SII) for Predicting the Survival of Patients with Stage I-III Gastric Cancer with a Signet-Ring Cell (SRC) Component
Table 2
The optimal cut-offs for prognostic factors according to ROC curves.
Variables
Threshold
Sensitivity
Specificity
AUC area (95% CI)
value
Tumor size
4.75
0.744
0.385
0.735 (0.692-0.778)
<0.001
Leukocyte
6.17
0.459
0.404
0.502 (0.452-0.552)
0.941
Neutrophil
3.27
0.537
0.452
0.539 (0.489-0.589)
0.130
Hemoglobin
121.2
0.793
0.653
0.578 (0.528-0.627)
0.002
Fibrinogen
3.06
0.583
0.381
0.617 (0.569-0.665)
<0.001
Prealbumin
234.5
0.637
0.384
0.662 (0.616-0.709)
<0.001
Albumin
42.5
0.500
0.351
0.587 (0.538-0.637)
0.001
Globulin
29.9
0.194
0.148
0.505 (0.454-0.555)
0.855
SII
527
0.438
0.244
0.615 (0.566-0.664)
<0.001
NLR
2.2
0.426
0.256
0.593 (0.544-0.643)
<0.001
PNI
48.73
0.752
0.550
0.615 (0.566-0.663)
<0.001
ROC: receiver operating characteristic; AUC: area under curve; CI: confidence interval; SII: systemic immune-inflammation index; PNI: prognostic nutritional index; NLR: lymphocyte to neutrophil ratio.
