Preoperative Systemic Immune-Inflammation Index (SII) for Predicting the Survival of Patients with Stage I-III Gastric Cancer with a Signet-Ring Cell (SRC) Component
Table 3
The correlation between the SII and other clinicopathological parameters.
Variables
(cases)
(cases)
value
Total
Sex
0.062
Men
230
102
Women
110
70
Age (years)
0.414
<55
159
87
≥55
181
85
SRCC
0.384
mSRCC
298
146
pSRCC
42
26
Chemotherapy
0.352
Yes
167
77
No
173
95
Tumor size (cm)
<0.001
<4.75
175
53
≥4.75
165
119
pT
<0.001
T1
74
10
T2
45
19
T3
39
23
T4
182
120
pN
<0.001
N0
127
39
N1
60
26
N2
67
33
N3a
60
42
N3b
26
32
pTNM
<0.001
I+II
173
47
III
167
125
Tumor location
0.079
Lower stomach
227
101
Middle stomach
49
26
Upper stomach
25
10
LM stomach
29
24
MU stomach
2
5
LMU stomach
8
6
Leukocyte
<0.001
<6.17
230
62
≥6.17
110
110
Neutrophil
<0.001
<3.27
231
29
≥3.27
109
143
Hemoglobin
<0.001
<121.2
60
80
≥121.2
280
92
Fibrinogen
<0.001
<3.06
204
64
≥3.06
136
108
Prealbumin
0.005
<234.5
149
98
≥234.5
191
74
Albumin
0.117
<42.5
187
82
≥42.5
153
90
Globulin
0.292
<29.9
278
147
≥29.9
62
25
PNI
<0.001
<48.73
92
84
≥48.73
248
88
Total gastrectomy
0.112
Yes
68
45
No
272
127
NLR
<0.001
<2.2
303
37
≥2.2
37
135
SII: systemic immune-inflammation index; SRCC: signet-ring cell carcinoma; pSRCC: pure signet-ring cell cancer; mSRCC: mixed signet-ring cell cancer; LM: lower and middle; MU: middle and upper; LMU: lower, middle, and upper; PNI: prognostic nutritional index; NLR: lymphocyte to neutrophil ratio.
