Preoperative Systemic Immune-Inflammation Index (SII) for Predicting the Survival of Patients with Stage I-III Gastric Cancer with a Signet-Ring Cell (SRC) Component
Table 5
Analysis of prognostic factors in 512 patients with gastric cancer with an SRC component by multivariate analysis.
B
SE
Sig
Exp(B)
95% CI for Exp(B)
Lower
Upper
T_COV_
-0.003
0.006
0.652
0.997
0.986
1.009
T_COV_1
-0.008
0.006
0.167
0.992
0.981
1.003
T-stage
0.688
0.126
<0.001
1.989
1.554
2.546
N-stage
0.413
0.075
<0.001
1.512
1.305
1.751
TNM stage
-0.241
0.269
0.370
0.786
0.464
1.331
Tumor size
0.134
0.163
0.410
1.143
0.831
1.573
Age
0.200
0.139
0.151
1.221
0.930
1.603
Neutrophil
-0.221
0.176
0.209
0.802
0.568
1.132
NLR
0.000
0.186
0.999
1.000
0.695
1.438
Hemoglobin
-0.001
0.151
0.996
0.999
0.744
1.342
SII
0.523
0.197
0.008
1.686
1.146
2.481
PNI
0.020
0.192
0.916
1.020
0.701
1.486
Albumin
-0.128
0.188
0.498
0.880
0.609
1.273
Total gastrectomy
-0.809
0.180
<0.001
0.446
0.313
0.633
Tumor location LMU
0.436
Tumor location L
0.431
0.352
0.222
1.538
0.771
3.068
Tumor location M
0.276
0.360
0.444
1.317
0.651
2.665
Tumor location U
0.650
0.384
0.091
1.915
0.901
4.068
Tumor location LM
0.136
0.361
0.707
1.145
0.565
2.323
Tumor location MU
0.384
0.561
0.494
1.468
0.489
4.405
SII: systemic immune-inflammation index; LM: lower and middle; MU: middle and upper; LMU: lower, middle, and upper; PNI: prognostic nutritional index; NLR: lymphocyte to neutrophil ratio; T_COV_: fibrinogen time-dependent variable; T_COV_1: prealbumin time-dependent variable.