Prediction of Protein-Protein Interactions with Local Weight-Sharing Mechanism in Deep Learning

Table 6

Performance comparisons on datasets for other species.

Species	Test set	Accuracy (%)	Recall (%)	Sensitivity (%)	Precision (%)	MCC (%)	AUC (%)
E. coli	1	95.29	91.22	99.35	99.29	90.88	95.29
	2	95.40	91.65	99.14	99.07	91.05	95.39
	3	95.40	91.94	98.85	98.76	91.01	95.39
	4	95.04	90.71	99.35	99.29	90.41	95.03
	5	95.22	91.07	99.35	99.29	90.75	95.21
	Hold-out	95.04	90.71	99.35	99.29	90.41	95.03
C. elegans	1	98.33	96.81	99.76	99.74	96.68	98.28
	2	98.20	96.56	99.76	99.74	96.44	98.16
	3	98.14	96.43	99.76	99.74	96.32	98.09
	4	98.33	97.19	99.40	99.35	96.67	98.30
	5	98.45	97.32	99.52	99.48	96.92	98.42
	Hold-out	98.14	96.81	99.40	99.35	96.30	98.10
S. cerevisiae	1	99.94	99.83	100.00	100.00	99.87	99.92
	2	99.99	99.97	100.00	100.00	99.98	99.99
	3	99.88	99.83	99.91	99.83	99.74	99.87
	4	99.99	99.97	100.00	100.00	99.98	99.99
	5	99.96	99.92	99.98	99.97	99.91	99.95
	Hold-out	99.86	99.61	100.00	100.00	99.70	99.80
Human	1	99.93	99.88	99.97	99.97	99.85	99.93
	2	99.92	99.86	99.97	99.97	99.84	99.92
	3	99.87	99.84	99.91	99.90	99.74	99.87
	4	99.89	99.84	99.93	99.93	99.77	99.88
	5	99.86	99.82	99.91	99.90	99.73	99.86
	Hold-out	99.94	99.88	100.00	100.00	99.88	99.94