A System Biology-Based Approach for Designing Combination Therapy in Cancer Precision Medicine

Table 2

Summary of target groups in cancer therapies and hypothesized relations with ABSM’s parameters.

Target group	Related parameters	Therapeutic type examples	Drug type examples
A		Monoclonal antibodies, chemotherapy/radiotherapy, small molecules	Bevacizumab [30], sunitinib [31]
B	,	Monoclonal antibodies, endocrine therapy	Trastuzumab [32], tamoxifen [33]
C	Age	Small molecules	Erlotinib [34]
D	,,	Chemotherapy/radiotherapy	Different types
E	,	Chemotherapy/radiotherapy	Different types